Preventing Recurrent C. Difficile Infections
Join us in a study to see how well a new treatment can help prevent C. difficile infections from coming back in adults aged 18 and older.
Study site: NeoClinical Research
- Clostridioides Difficile Infection
Recruiting
Male/Female
18+ years of age
TBD
- About the Study
- We’re looking for about 230 participants who will be randomly assigned to receive either the treatment or a placebo (a harmless solution). You may receive the treatment through an injection in your muscle or a quick push into your vein, based on what the doctor thinks is best. Here’s what to expect: * Up to 2 visits to confirm eligibility and receive the treatment, including a stool sample collection; * Up to 7 follow-up visits; * Regular check-ins from our team, starting weekly and then monthly; * You’ll keep track of your health in an electronic diary.
- What does the study involve?
- You will receive a single dose of the treatment through an injection in your muscle or a quick push into your vein. Some participants will receive a placebo (a harmless solution) in the same way.
What to expect
- Placebo
- You may receive a placebo (a look-alike with no active medicine).
- Which treatment you get
- Chosen at random. Neither you nor the study team will know which treatment you get.
- Who can participate?
- We’re looking for adults aged 18 and older who: * Have had a recent C. difficile infection with specific symptoms and a positive test result; * Are starting treatment with antibiotics for this infection; * Weigh at least 35 kg (about 77 lbs). Not everyone will qualify, so if you think you might fit, apply to find out more!
Where is the study taking place?
Palmetto Medical Plaza
Study details
- Sponsor
- AstraZeneca
- Phase
- Phase 2: testing whether it works, and its safety, in a larger group
- Dates
- December 2025 to January 2028 (expected)
- Size
- 230 participants across all sites
- Healthy volunteers
- Only people with the condition
Study details are from ClinicalTrials.gov. The rest of this page is written by the study site for patients and may summarize or reword the registry record, which is the official text. A study listed on ClinicalTrials.gov has not necessarily been reviewed or approved by the U.S. government.
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About NeoClinical Research
NeoClinical Research is a leading, multi-therapeutic clinical research center based in South Florida that bridges the gap between leading pharmaceutical companies and diverse patient populations.