Clinical trials near you

Clinical trials in the Denver area

1,451 studies are recruiting volunteers at 659 research sites in the Denver-Aurora-Centennial, CO area.

Sites in Aurora, Denver, Englewood, Lone Tree, Littleton, Golden and 7 more towns.

#12 in the US for recruiting studies#1 in Colorado#20 in the US per resident

Studies recruiting
1,451
Research sites
659
Conditions studied
197
Studies per 100,000 residents
47.5

Conditions being studied

The conditions with the most studies recruiting in the area. A study can be for more than one condition.

  • Lung cancer98 studies
  • Breast cancer72 studies
  • Colorectal cancer (bowel cancer)68 studies
  • Leukemia57 studies
  • Head and neck cancer46 studies
  • Non-Hodgkin's lymphoma45 studies
  • Prostate cancer44 studies
  • Ovarian cancer40 studies
  • Neuroendocrine tumor39 studies
  • Uterine cancer36 studies
  • Melanoma33 studies
  • Multiple myeloma (MM)33 studies
  • Skin cancer33 studies
  • Endometrial cancer31 studies
  • Liver disease30 studies
All 197 conditions
  • Lung cancer98
  • Breast cancer72
  • Colorectal cancer (bowel cancer)68
  • Leukemia57
  • Head and neck cancer46
  • Non-Hodgkin's lymphoma45
  • Prostate cancer44
  • Ovarian cancer40
  • Neuroendocrine tumor39
  • Uterine cancer36
  • Melanoma33
  • Multiple myeloma (MM)33
  • Skin cancer33
  • Endometrial cancer31
  • Liver disease30
  • Type 1 diabetes27
  • Overweight and obesity25
  • Kidney cancer24
  • Pancreatic cancer24
  • Type 2 diabetes24
  • Gastric cancer (stomach cancer)23
  • Bladder cancer22
  • Esophageal cancer21
  • High blood pressure (hypertension)20
  • Interstitial lung disease20
  • Peripheral nerve disease20
  • Sarcoma of soft tissue20
  • Brain cancer19
  • Chronic kidney disease (CKD)18
  • Cystic fibrosis18
  • Heart failure18
  • Inflammatory bowel disease (IBD)16
  • Parkinson's disease (PD)16
  • Age-related macular degeneration (AMD)15
  • Depressive disorder15
  • Retinal degeneration15
  • Cardiovascular disease14
  • Congenital heart disease14
  • Intellectual disability14
  • Liver cancer14
  • Pulmonary hypertension14
  • Chronic obstructive pulmonary disease (COPD)13
  • Myelodysplastic syndrome (MDS)13
  • Anxiety disorder12
  • Biliary tract cancer12
  • Cervical cancer12
  • Multiple sclerosis (MS)12
  • Rheumatoid arthritis12
  • Systemic lupus erythematosus (SLE)12
  • Alzheimer's disease11
  • Asthma11
  • Ischemic heart disease (IHD)11
  • Atrial fibrillation (AF)10
  • Crohn's disease10
  • Fallopian tube cancer10
  • Human immunodeficiency virus infection (HIV)10
  • Migraine10
  • Ulcerative colitis (UC)9
  • Cardiomyopathy8
  • Down syndrome8
  • Epilepsy8
  • Neuroblastoma8
  • Post-traumatic stress disorder (PTSD)8
  • Stroke8
  • Thrombocytopenia8
  • Amyloidosis7
  • Fatty liver disease (MASH/NASH)7
  • Motor neuron disease (MND)7
  • Myelofibrosis7
  • Peripheral vascular disease7
  • Bile duct cancer6
  • COVID-196
  • Hearing loss6
  • Hodgkin's lymphoma6
  • Osteoarthritis (OA)6
  • Scoliosis6
  • Alcohol dependence5
  • Amyotrophic lateral sclerosis (ALS)5
  • Anemia5
  • Cannabis use disorder5
  • Insomnia5
  • Menopause symptoms5
  • Peritoneal cancer5
  • Psoriasis5
  • Systemic sclerosis5
  • Thrombotic microangiopathy5
  • Traumatic brain injury5
  • Abdominal cancer4
  • Birth control (contraception)4
  • Eczema (atopic dermatitis)4
  • Food allergy4
  • Gallbladder cancer4
  • Gastrointestinal stromal tumor4
  • Graft-versus-host disease4
  • Growth hormone deficiency4
  • Macular edema4
  • Rhabdomyosarcoma4
  • Thyroid cancer4
  • Vasculitis4
  • Autism spectrum disorder (ASD)3
  • Diabetic eye disease3
  • Esophagitis3
  • Hemophilia A3
  • Huntington's disease (HD)3
  • Idiopathic inflammatory myopathy3
  • Influenza (flu)3
  • Opioid use disorder3
  • Osteoporosis3
  • Phenylketonuria (PKU)3
  • Postnatal depression3
  • Primary sclerosing cholangitis3
  • Progressive supranuclear palsy (PSP)3
  • Psoriatic arthritis (PsA)3
  • Rett's disorder3
  • Sleep apnea3
  • Smoking dependence3
  • Stargardt's disease3
  • Testicular cancer3
  • Ureteral cancer3
  • Urinary incontinence3
  • Abdominal aortic aneurysm2
  • Alopecia2
  • Alopecia areata2
  • Anal cancer2
  • Attention-deficit hyperactivity disorder (ADHD)2
  • Axial spondyloarthritis2
  • Cutaneous T-cell lymphoma2
  • Epidermolysis bullosa2
  • Essential thrombocythemia (ET)2
  • Familial multiple polyposis syndrome2
  • Female infertility2
  • Friedreich ataxia2
  • Frontotemporal dementia (FTD)2
  • Glaucoma2
  • Gout2
  • Graves' disease2
  • Hemolytic uremic syndrome2
  • Hypercholesterolemia2
  • Immune thrombocytopenic purpura (ITP)2
  • Neurofibromatosis2
  • Neurofibromatosis type 1 (NF1)2
  • Neuromyelitis optica spectrum disorder (NMOSD)2
  • Neuropathic pain2
  • Ocular hypertension2
  • Polycystic ovarian syndrome (PCOS)2
  • Polycythemia vera2
  • Rhabdoid tumor2
  • Rotator cuff syndrome2
  • RSV infection2
  • Schizophrenia2
  • Spinal muscular atrophy (SMA)2
  • Vascular dementia2
  • Achondroplasia1
  • Actinic keratosis1
  • Acute coronary syndrome1
  • Alpha-1-antitrypsin deficiency (AATD)1
  • Ankylosing spondylitis1
  • Bipolar disorder1
  • Bone cyst1
  • Cancer of unknown primary site (CUP)1
  • Celiac disease1
  • Chronic cough1
  • Chronic sinusitis1
  • Dry eye syndrome1
  • Duchenne muscular dystrophy (DMD)1
  • Eating disorder1
  • Endometriosis1
  • Fabry's disease1
  • Facioscapulohumeral muscular dystrophy1
  • Fragile X syndrome1
  • Germ cell tumor1
  • Hemophilia B1
  • Hepatitis C1
  • Hereditary angioedema1
  • Hidradenitis suppurativa (HS)1
  • Hypertriglyceridemia1
  • Hypothyroidism1
  • Irritable bowel syndrome (IBS)1
  • Juvenile idiopathic arthritis (JIA)1
  • Low back pain1
  • Pericarditis1
  • Polymyalgia rheumatica1
  • Pompe disease1
  • Post-transplant lymphoproliferative disorder1
  • Prader-Willi syndrome1
  • Primary biliary cholangitis (PBC)1
  • Primary hyperoxaluria1
  • Prurigo nodularis1
  • Psychotic disorder1
  • Sickle cell disease1
  • Sjogren's syndrome1
  • Spasmodic torticollis1
  • Tricuspid valve regurgitation1
  • Tuberculosis1
  • Urethral cancer1
  • Vaginal cancer1
  • Wilson's disease1

410 more studies are for conditions not yet in our catalog.

Whom the studies accept

The share of the area's studies open to each group. A study can accept several.

  • Adults 18 to 6493%
  • Adults 65 and over79%
  • Children and teens (under 18)27%
  • Healthy volunteers10%
  • Open to all sexes91%
  • Women only6%
  • Men only3%

92 studies are for children only.

Study phases

Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.

  • Early phase 10%
  • Phase 110%
  • Phase 1/29%
  • Phase 217%
  • Phase 2/33%
  • Phase 325%
  • Phase 43%
  • No phase (device, behavioral and other studies)16%
  • Not stated17%

Most active research sites

The sites recruiting for the most studies in the area.

  1. University of Colorado Anschutz Medical CampusAurora514 studies
  2. Children's Hospital ColoradoAurora199 studies
  3. Sarah Cannon Research Institute at HealthONEDenver58 studies
  4. Colorado Blood Cancer InstituteDenver57 studies
  5. National Jewish HealthDenver42 studies
  6. Rocky Mountain Cancer CentersAurora39 studies
  7. Rocky Mountain Regional VA Medical Center, Aurora, COAurora37 studies
  8. Rocky Mountain Cancer CentersLone Tree33 studies
  9. UCHealth Highlands Ranch HospitalLittleton32 studies
  10. Rocky Mountain Cancer Centers, LLPDenver28 studies
  11. CommonSpirit Saint Anthony Hospital Cancer CenterDenver27 studies
  12. Saint Anthony North HospitalBroomfield24 studies
  13. The Children's Hospital of ColoradoAurora21 studies
  14. UCHealth - Cherry CreekDenver19 studies
  15. Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical CenterDenver18 studies

Cite these figures

Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.

As text

Source: LocalTrial, Clinical trials in the Denver area, https://www.localtrial.com/clinical-trials/colorado/denver, updated November 12, 2026.

With the link, for a web page

Source: <a href="https://www.localtrial.com/clinical-trials/colorado/denver">LocalTrial, Clinical trials in the Denver area</a>, updated November 12, 2026.

About these figures

Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.

The area is the U.S. Census Bureau's Denver-Aurora-Centennial, CO metropolitan area. Residents: 3,052,498, the Census Bureau's latest estimate. Updated November 12, 2026.

These figures describe studies, not advice. Talk to your doctor before joining one.

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