Clinical trials near you

Clinical trials in the Chicago area

2,378 studies are recruiting volunteers at 1,221 research sites in the Chicago-Naperville-Elgin, IL-IN area.

Sites in Chicago, Evanston, Skokie, Naperville, Glenview, Oak Lawn and 34 more towns.

#5 in the US for recruiting studies#1 in Illinois#87 in the US per resident

Studies recruiting
2,378
Research sites
1,221
Conditions studied
213
Studies per 100,000 residents
25.3

Conditions being studied

The conditions with the most studies recruiting in the area. A study can be for more than one condition.

  • Lung cancer139 studies
  • Breast cancer103 studies
  • Leukemia81 studies
  • Non-Hodgkin's lymphoma73 studies
  • Colorectal cancer (bowel cancer)66 studies
  • Prostate cancer66 studies
  • Head and neck cancer60 studies
  • Overweight and obesity56 studies
  • Liver disease53 studies
  • Stroke51 studies
  • Ovarian cancer47 studies
  • Heart failure44 studies
  • Uterine cancer39 studies
  • Inflammatory bowel disease (IBD)38 studies
  • Depressive disorder37 studies
All 213 conditions
  • Lung cancer139
  • Breast cancer103
  • Leukemia81
  • Non-Hodgkin's lymphoma73
  • Colorectal cancer (bowel cancer)66
  • Prostate cancer66
  • Head and neck cancer60
  • Overweight and obesity56
  • Liver disease53
  • Stroke51
  • Ovarian cancer47
  • Heart failure44
  • Uterine cancer39
  • Inflammatory bowel disease (IBD)38
  • Depressive disorder37
  • Pancreatic cancer37
  • Bladder cancer36
  • Multiple myeloma (MM)35
  • Endometrial cancer33
  • High blood pressure (hypertension)33
  • Type 2 diabetes33
  • Neuroendocrine tumor30
  • Peripheral nerve disease30
  • Cardiovascular disease26
  • Chronic kidney disease (CKD)25
  • Schizophrenia25
  • Brain cancer24
  • Human immunodeficiency virus infection (HIV)24
  • Sarcoma of soft tissue24
  • Skin cancer24
  • Anemia23
  • Atrial fibrillation (AF)23
  • Kidney cancer23
  • Liver cancer23
  • Osteoarthritis (OA)23
  • Ulcerative colitis (UC)23
  • Chronic obstructive pulmonary disease (COPD)22
  • Gastric cancer (stomach cancer)22
  • Melanoma22
  • Age-related macular degeneration (AMD)21
  • Retinal degeneration21
  • Alzheimer's disease20
  • Crohn's disease19
  • Esophageal cancer19
  • Interstitial lung disease19
  • Ischemic heart disease (IHD)19
  • Multiple sclerosis (MS)19
  • Myelodysplastic syndrome (MDS)19
  • Anxiety disorder18
  • Sickle cell disease18
  • Parkinson's disease (PD)17
  • Systemic lupus erythematosus (SLE)17
  • Type 1 diabetes17
  • COVID-1916
  • Rheumatoid arthritis15
  • Cervical cancer14
  • Cardiomyopathy13
  • Motor neuron disease (MND)13
  • Peripheral vascular disease13
  • Fallopian tube cancer12
  • Sleep apnea12
  • Post-traumatic stress disorder (PTSD)11
  • Fatty liver disease (MASH/NASH)10
  • Intellectual disability10
  • Amyotrophic lateral sclerosis (ALS)9
  • Cystic fibrosis9
  • Eczema (atopic dermatitis)9
  • Epilepsy9
  • Graft-versus-host disease9
  • Influenza (flu)9
  • Low back pain9
  • Myelofibrosis9
  • Biliary tract cancer8
  • Chronic skin ulcer8
  • Congenital heart disease8
  • Neuropathic pain8
  • Systemic sclerosis8
  • Traumatic brain injury8
  • Autism spectrum disorder (ASD)7
  • Bipolar disorder7
  • Diabetic eye disease7
  • Migraine7
  • Neuroblastoma7
  • Psoriasis7
  • Urinary incontinence7
  • Abdominal aortic aneurysm6
  • Alopecia6
  • Amyloidosis6
  • Asthma6
  • Dry eye syndrome6
  • Hidradenitis suppurativa (HS)6
  • Hodgkin's lymphoma6
  • Idiopathic inflammatory myopathy6
  • Opioid use disorder6
  • Overactive bladder (OAB)6
  • Peritoneal cancer6
  • Phenylketonuria (PKU)6
  • Psychotic disorder6
  • Pulmonary hypertension6
  • Rotator cuff syndrome6
  • Smoking dependence6
  • Abdominal cancer5
  • Alopecia areata5
  • Bile duct cancer5
  • Down syndrome5
  • Duchenne muscular dystrophy (DMD)5
  • Gastrointestinal stromal tumor5
  • Insomnia5
  • Post-transplant lymphoproliferative disorder5
  • Psoriatic arthritis (PsA)5
  • Sjogren's syndrome5
  • Spinal muscular atrophy (SMA)5
  • Tricuspid valve regurgitation5
  • Alcohol dependence4
  • Anal cancer4
  • Chronic idiopathic urticaria (hives)4
  • Cutaneous T-cell lymphoma4
  • Essential thrombocythemia (ET)4
  • Fabry's disease4
  • Hearing loss4
  • Hypercholesterolemia4
  • Pericarditis4
  • Schizoaffective disorder4
  • Thrombocytopenia4
  • Axial spondyloarthritis3
  • Celiac disease3
  • Cerebral palsy3
  • Epidermolysis bullosa3
  • Esophagitis3
  • Food allergy3
  • Frontotemporal dementia (FTD)3
  • Gallbladder cancer3
  • Germ cell tumor3
  • Gout3
  • Graves' disease3
  • Hemophilia A3
  • Hepatitis C3
  • Huntington's disease (HD)3
  • Macular edema3
  • Neurofibromatosis3
  • Neurofibromatosis type 1 (NF1)3
  • Postnatal depression3
  • Radiculopathy3
  • Short-sightedness (myopia)3
  • Testicular cancer3
  • Thyroid cancer3
  • Ureteral cancer3
  • Vascular dementia3
  • Vasculitis3
  • Acne2
  • Actinic keratosis2
  • Bone cancer2
  • Complex regional pain syndrome (CRPS)2
  • Familial multiple polyposis syndrome2
  • Gestational diabetes2
  • Hemophilia B2
  • Hereditary angioedema2
  • Immune thrombocytopenic purpura (ITP)2
  • Irritable bowel syndrome (IBS)2
  • Juvenile idiopathic arthritis (JIA)2
  • Osteoporosis2
  • Polycythemia vera2
  • Primary sclerosing cholangitis2
  • Progressive supranuclear palsy (PSP)2
  • Rett's disorder2
  • Rhabdomyosarcoma2
  • Scoliosis2
  • Spasmodic torticollis2
  • Thrombotic microangiopathy2
  • Thyroid eye disease2
  • Urethral cancer2
  • Vaginal cancer2
  • Vitiligo2
  • Achondroplasia1
  • Acromegaly1
  • Acute coronary syndrome1
  • Alpha-1-antitrypsin deficiency (AATD)1
  • Ankylosing spondylitis1
  • Attention-deficit hyperactivity disorder (ADHD)1
  • Atypical endometrial hyperplasia1
  • Birth control (contraception)1
  • Bone cyst1
  • Cancer of unknown primary site (CUP)1
  • Carpal tunnel syndrome1
  • Dysmenorrhea1
  • Endometriosis1
  • Female infertility1
  • Fibromyalgia1
  • Fragile X syndrome1
  • Friedreich ataxia1
  • Glaucoma1
  • Hepatitis B1
  • Long QT syndrome1
  • Menopause symptoms1
  • Narcolepsy1
  • Neuromyelitis optica spectrum disorder (NMOSD)1
  • Ocular hypertension1
  • Pemphigus vulgaris1
  • Polycystic ovarian syndrome (PCOS)1
  • Polymyalgia rheumatica1
  • Pompe disease1
  • Prader-Willi syndrome1
  • Primary biliary cholangitis (PBC)1
  • Primary hyperoxaluria1
  • Prurigo nodularis1
  • Recurrent urinary tract infection (UTI)1
  • Rhabdoid tumor1
  • RSV infection1
  • Stargardt's disease1
  • Tear of meniscus of knee1
  • Vulvar cancer1
  • Vulvovaginal candidiasis (thrush)1
  • Wilson's disease1

710 more studies are for conditions not yet in our catalog.

Whom the studies accept

The share of the area's studies open to each group. A study can accept several.

  • Adults 18 to 6494%
  • Adults 65 and over84%
  • Children and teens (under 18)21%
  • Healthy volunteers11%
  • Open to all sexes91%
  • Women only5%
  • Men only3%

135 studies are for children only.

Study phases

Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.

  • Early phase 11%
  • Phase 17%
  • Phase 1/26%
  • Phase 218%
  • Phase 2/33%
  • Phase 324%
  • Phase 43%
  • No phase (device, behavioral and other studies)23%
  • Not stated16%

Most active research sites

The sites recruiting for the most studies in the area.

  1. University of ChicagoChicago523 studies
  2. Northwestern UniversityChicago440 studies
  3. University of IllinoisChicago230 studies
  4. Ann & Robert H. Lurie Children's Hospital of ChicagoChicago161 studies
  5. Rush University Medical CenterChicago155 studies
  6. Loyola University Medical CenterMaywood91 studies
  7. Northwestern Memorial HospitalChicago74 studies
  8. Northwestern Medicine Cancer Center WarrenvilleWarrenville68 studies
  9. NorthShore University HealthSystem-Evanston HospitalEvanston67 studies
  10. Northwestern Medicine Cancer Center DelnorGeneva64 studies
  11. Northwestern Medicine Cancer Center KishwaukeeDekalb64 studies
  12. Advocate Lutheran General HospitalPark Ridge59 studies
  13. Advocate Christ Medical CenterOak Lawn56 studies
  14. Northwestern Medicine Orland ParkOrland Park56 studies
  15. Northwestern Medicine Lake Forest HospitalLake Forest52 studies

Cite these figures

Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.

As text

Source: LocalTrial, Clinical trials in the Chicago area, https://www.localtrial.com/clinical-trials/illinois/chicago, updated November 12, 2026.

With the link, for a web page

Source: <a href="https://www.localtrial.com/clinical-trials/illinois/chicago">LocalTrial, Clinical trials in the Chicago area</a>, updated November 12, 2026.

About these figures

Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.

The area is the U.S. Census Bureau's Chicago-Naperville-Elgin, IL-IN metropolitan area. Residents: 9,408,576, the Census Bureau's latest estimate. Updated November 12, 2026.

These figures describe studies, not advice. Talk to your doctor before joining one.

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