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Clinical trials in the Portland area

155 studies are recruiting volunteers at 77 research sites in the Portland-South Portland, ME area.

Sites in Scarborough, Portland, South Portland, Brunswick, Sanford, Biddeford and 9 more towns.

#97 in the US for recruiting studies#1 in Maine#76 in the US per resident

Studies recruiting
155
Research sites
77
Conditions studied
72
Studies per 100,000 residents
27.1

Conditions being studied

The conditions with the most studies recruiting in the area. A study can be for more than one condition.

  • Leukemia20 studies
  • Lung cancer19 studies
  • Breast cancer15 studies
  • Non-Hodgkin's lymphoma10 studies
  • Ovarian cancer9 studies
  • Colorectal cancer (bowel cancer)8 studies
  • Uterine cancer8 studies
  • Endometrial cancer6 studies
  • Head and neck cancer6 studies
  • Kidney cancer6 studies
  • Prostate cancer6 studies
  • Sarcoma of soft tissue5 studies
  • Atrial fibrillation (AF)4 studies
  • Heart failure4 studies
  • Melanoma4 studies
All 72 conditions
  • Leukemia20
  • Lung cancer19
  • Breast cancer15
  • Non-Hodgkin's lymphoma10
  • Ovarian cancer9
  • Colorectal cancer (bowel cancer)8
  • Uterine cancer8
  • Endometrial cancer6
  • Head and neck cancer6
  • Kidney cancer6
  • Prostate cancer6
  • Sarcoma of soft tissue5
  • Atrial fibrillation (AF)4
  • Heart failure4
  • Melanoma4
  • Myelodysplastic syndrome (MDS)4
  • Neuroendocrine tumor4
  • Skin cancer4
  • Age-related macular degeneration (AMD)3
  • Cardiovascular disease3
  • Cervical cancer3
  • Esophageal cancer3
  • Fallopian tube cancer3
  • Gastric cancer (stomach cancer)3
  • Multiple myeloma (MM)3
  • Overweight and obesity3
  • Retinal degeneration3
  • Abdominal aortic aneurysm2
  • Bladder cancer2
  • Cystic fibrosis2
  • Inflammatory bowel disease (IBD)2
  • Liver disease2
  • Neuroblastoma2
  • Pancreatic cancer2
  • Rhabdomyosarcoma2
  • Stroke2
  • Ulcerative colitis (UC)2
  • Abdominal cancer1
  • Alzheimer's disease1
  • Anemia1
  • Attention-deficit hyperactivity disorder (ADHD)1
  • Autism spectrum disorder (ASD)1
  • Bile duct cancer1
  • Brain cancer1
  • Cardiomyopathy1
  • Celiac disease1
  • COVID-191
  • Crohn's disease1
  • Diabetic eye disease1
  • Down syndrome1
  • Fabry's disease1
  • Germ cell tumor1
  • Hemophilia A1
  • Hemophilia B1
  • High blood pressure (hypertension)1
  • Hodgkin's lymphoma1
  • Intellectual disability1
  • Ischemic heart disease (IHD)1
  • Liver cancer1
  • Myelofibrosis1
  • Opioid use disorder1
  • Osteoporosis1
  • Parkinson's disease (PD)1
  • Peripheral vascular disease1
  • Peritoneal cancer1
  • Pompe disease1
  • Post-transplant lymphoproliferative disorder1
  • Pulmonary hypertension1
  • Sickle cell disease1
  • Testicular cancer1
  • Tricuspid valve regurgitation1
  • Type 1 diabetes1

28 more studies are for conditions not yet in our catalog.

Whom the studies accept

The share of the area's studies open to each group. A study can accept several.

  • Adults 18 to 6497%
  • Adults 65 and over81%
  • Children and teens (under 18)26%
  • Healthy volunteers5%
  • Open to all sexes90%
  • Women only8%
  • Men only3%

3 studies are for children only.

Study phases

Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.

  • Phase 11%
  • Phase 1/22%
  • Phase 217%
  • Phase 2/36%
  • Phase 346%
  • Phase 43%
  • No phase (device, behavioral and other studies)11%
  • Not stated14%

Most active research sites

The sites recruiting for the most studies in the area.

  1. MaineHealth Maine Medical Center - PortlandPortland46 studies
  2. MaineHealth Maine Medical Center- ScarboroughScarborough41 studies
  3. MaineHealth Cancer Care and IV Therapy - South PortlandSouth Portland31 studies
  4. Maine Children's Cancer ProgramScarborough25 studies
  5. MaineHealth Cancer Care Center of York CountySanford21 studies
  6. MaineHealth Cancer Care and IV Therapy - BrunswickBrunswick15 studies
  7. New England Cancer SpecialistsWestbrook14 studies
  8. MaineHealth Cancer Care and IV Therapy - SanfordSanford9 studies
  9. MaineHealth Coastal Cancer Treatment CenterBath9 studies
  10. Mid Coast HospitalBrunswick8 studies
  11. New England Cancer SpecialistsScarborough7 studies
  12. Maine Eye CenterPortland4 studies
  13. Maine Medical Center- Scarborough CampusScarborough4 studies
  14. Maine Medical Partners Pediatric Specialty CarePortland4 studies
  15. New England Cancer Specialists - TopshamTopsham4 studies

Cite these figures

Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.

As text

Source: LocalTrial, Clinical trials in the Portland area, https://www.localtrial.com/clinical-trials/maine/portland, updated November 12, 2026.

With the link, for a web page

Source: <a href="https://www.localtrial.com/clinical-trials/maine/portland">LocalTrial, Clinical trials in the Portland area</a>, updated November 12, 2026.

About these figures

Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.

The area is the U.S. Census Bureau's Portland-South Portland, ME metropolitan area. Residents: 571,534, the Census Bureau's latest estimate. Updated November 12, 2026.

These figures describe studies, not advice. Talk to your doctor before joining one.

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