Clinical trials near you
Clinical trials in the St. Louis area
1,415 studies are recruiting volunteers at 529 research sites in the St. Louis, MO-IL area.
Sites in Saint Louis, Chesterfield, O Fallon, Saint Charles, Bridgeton, Hazelwood and 19 more towns.
#13 in the US for recruiting studies#1 in Missouri#18 in the US per resident
- Studies recruiting
- 1,415
- Research sites
- 529
- Conditions studied
- 182
- Studies per 100,000 residents
- 50.3
Conditions being studied
The conditions with the most studies recruiting in the area. A study can be for more than one condition.
- Lung cancer102 studies
- Breast cancer91 studies
- Colorectal cancer (bowel cancer)67 studies
- Head and neck cancer66 studies
- Prostate cancer52 studies
- Leukemia45 studies
- Non-Hodgkin's lymphoma45 studies
- Pancreatic cancer41 studies
- Uterine cancer39 studies
- Ovarian cancer37 studies
- Neuroendocrine tumor36 studies
- Kidney cancer35 studies
- Liver disease34 studies
- Overweight and obesity34 studies
- Endometrial cancer31 studies
All 182 conditions
- Lung cancer102
- Breast cancer91
- Colorectal cancer (bowel cancer)67
- Head and neck cancer66
- Prostate cancer52
- Leukemia45
- Non-Hodgkin's lymphoma45
- Pancreatic cancer41
- Uterine cancer39
- Ovarian cancer37
- Neuroendocrine tumor36
- Kidney cancer35
- Liver disease34
- Overweight and obesity34
- Endometrial cancer31
- Inflammatory bowel disease (IBD)31
- Multiple myeloma (MM)28
- Bladder cancer26
- Brain cancer26
- Sarcoma of soft tissue26
- Skin cancer26
- Alzheimer's disease25
- Depressive disorder25
- Heart failure25
- Melanoma23
- Peripheral nerve disease23
- Esophageal cancer22
- Anemia21
- Stroke21
- Cardiovascular disease20
- Crohn's disease20
- Gastric cancer (stomach cancer)19
- Liver cancer17
- Myelodysplastic syndrome (MDS)16
- Ulcerative colitis (UC)16
- Cervical cancer13
- Multiple sclerosis (MS)13
- Chronic kidney disease (CKD)12
- Congenital heart disease12
- Sickle cell disease12
- Cardiomyopathy11
- Fallopian tube cancer11
- Fatty liver disease (MASH/NASH)11
- Schizophrenia11
- Type 2 diabetes11
- Atrial fibrillation (AF)10
- Parkinson's disease (PD)10
- Age-related macular degeneration (AMD)9
- Asthma9
- Cystic fibrosis9
- Motor neuron disease (MND)9
- Myelofibrosis9
- Neuroblastoma9
- Retinal degeneration9
- Amyotrophic lateral sclerosis (ALS)8
- Chronic obstructive pulmonary disease (COPD)8
- Chronic skin ulcer8
- Ischemic heart disease (IHD)8
- Amyloidosis7
- Graft-versus-host disease7
- High blood pressure (hypertension)7
- Intellectual disability7
- Post-traumatic stress disorder (PTSD)7
- Systemic lupus erythematosus (SLE)7
- Anxiety disorder6
- Influenza (flu)6
- Interstitial lung disease6
- Down syndrome5
- Human immunodeficiency virus infection (HIV)5
- Migraine5
- Pompe disease5
- Pulmonary hypertension5
- Sleep apnea5
- Abdominal aortic aneurysm4
- Autism spectrum disorder (ASD)4
- Biliary tract cancer4
- Bipolar disorder4
- COVID-194
- Endometriosis4
- Epilepsy4
- Essential thrombocythemia (ET)4
- Familial multiple polyposis syndrome4
- Hemophilia A4
- Hereditary angioedema4
- Hidradenitis suppurativa (HS)4
- Idiopathic inflammatory myopathy4
- Low back pain4
- Narcolepsy4
- Psoriasis4
- Rheumatoid arthritis4
- Traumatic brain injury4
- Type 1 diabetes4
- Urinary incontinence4
- Abdominal cancer3
- Bile duct cancer3
- Cutaneous T-cell lymphoma3
- Duchenne muscular dystrophy (DMD)3
- Eating disorder3
- Germ cell tumor3
- Hodgkin's lymphoma3
- Hypercholesterolemia3
- Insomnia3
- Neuropathic pain3
- Osteoarthritis (OA)3
- Post-transplant lymphoproliferative disorder3
- Psoriatic arthritis (PsA)3
- Psychotic disorder3
- Recurrent urinary tract infection (UTI)3
- Rhabdoid tumor3
- Rhabdomyosarcoma3
- Systemic sclerosis3
- Thrombocytopenia3
- Thrombotic microangiopathy3
- Thyroid cancer3
- Bone cancer2
- Diabetic eye disease2
- Dry eye syndrome2
- Eczema (atopic dermatitis)2
- Fabry's disease2
- Fibromyalgia2
- Gastrointestinal stromal tumor2
- Glaucoma2
- Graves' disease2
- Hearing loss2
- Hemolytic uremic syndrome2
- Hemophilia B2
- Hypertriglyceridemia2
- Juvenile idiopathic arthritis (JIA)2
- Macular edema2
- Neurofibromatosis2
- Neurofibromatosis type 1 (NF1)2
- Ocular hypertension2
- Overactive bladder (OAB)2
- Pericarditis2
- Peripheral vascular disease2
- Peritoneal cancer2
- Polymyalgia rheumatica2
- Primary sclerosing cholangitis2
- Smoking dependence2
- Spinal muscular atrophy (SMA)2
- Ureteral cancer2
- Vasculitis2
- Achondroplasia1
- Acromegaly1
- Acute coronary syndrome1
- Allergic rhinitis (hay fever)1
- Alopecia1
- Alpha-1-antitrypsin deficiency (AATD)1
- Anal cancer1
- Attention-deficit hyperactivity disorder (ADHD)1
- Atypical endometrial hyperplasia1
- Axial spondyloarthritis1
- Celiac disease1
- Chronic idiopathic urticaria (hives)1
- Complex regional pain syndrome (CRPS)1
- Friedreich ataxia1
- Frontotemporal dementia (FTD)1
- Gestational diabetes1
- Gout1
- Hepatitis C1
- Huntington's disease (HD)1
- Irritable bowel syndrome (IBS)1
- Long QT syndrome1
- Menopause symptoms1
- Neuromyelitis optica spectrum disorder (NMOSD)1
- Obsessive-compulsive disorder (OCD)1
- Opioid use disorder1
- Osteoporosis1
- Polycythemia vera1
- Primary hyperoxaluria1
- Progressive supranuclear palsy (PSP)1
- Prurigo nodularis1
- Rett's disorder1
- RSV infection1
- Schizoaffective disorder1
- Scoliosis1
- Sjogren's syndrome1
- Spasmodic torticollis1
- Tenosynovitis1
- Testicular cancer1
- Tuberous sclerosis1
- Urethral cancer1
326 more studies are for conditions not yet in our catalog.
Whom the studies accept
The share of the area's studies open to each group. A study can accept several.
- Adults 18 to 6495%
- Adults 65 and over86%
- Children and teens (under 18)20%
- Healthy volunteers8%
- Open to all sexes92%
- Women only5%
- Men only3%
53 studies are for children only.
Study phases
Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.
- Early phase 11%
- Phase 19%
- Phase 1/28%
- Phase 221%
- Phase 2/33%
- Phase 327%
- Phase 42%
- No phase (device, behavioral and other studies)16%
- Not stated14%
Most active research sites
The sites recruiting for the most studies in the area.
- Washington University School of MedicineSaint Louis744 studies
- Mercy Hospital Saint LouisSaint Louis95 studies
- Cancer Care Center of O'FallonO Fallon88 studies
- Washington UniversitySaint Louis76 studies
- Mercy Hospital SouthSaint Louis75 studies
- Missouri Baptist Medical CenterSaint Louis75 studies
- Siteman Cancer Center-South CountySaint Louis75 studies
- Siteman Cancer Center at Christian HospitalSaint Louis69 studies
- Siteman Cancer Center at West County HospitalSaint Louis69 studies
- Siteman Cancer Center at Saint Peters HospitalSaint Peters67 studies
- Missouri Baptist Sullivan HospitalSullivan61 studies
- HSHS Saint Elizabeth's HospitalO Fallon55 studies
- Memorial Hospital EastO Fallon52 studies
- Washington University School of MedicineSaint Louis39 studies
- Mercy Oncology and Hematology - Clayton-ClarksonBallwin35 studies
Cite these figures
Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.
Source: LocalTrial, Clinical trials in the St. Louis area, https://www.localtrial.com/clinical-trials/missouri/st-louis, updated November 12, 2026.
Source: <a href="https://www.localtrial.com/clinical-trials/missouri/st-louis">LocalTrial, Clinical trials in the St. Louis area</a>, updated November 12, 2026.
About these figures
Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.
The area is the U.S. Census Bureau's St. Louis, MO-IL metropolitan area. Residents: 2,811,927, the Census Bureau's latest estimate. Updated November 12, 2026.
These figures describe studies, not advice. Talk to your doctor before joining one.
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