Clinical trials near you

Clinical trials in the Charlotte area

639 studies are recruiting volunteers at 399 research sites in the Charlotte-Concord-Gastonia, NC-SC area.

Sites in Charlotte, Huntersville, Rock Hill, Statesville, Salisbury, Matthews and 11 more towns.

#40 in the US for recruiting studies#2 in North Carolina#101 in the US per resident

Studies recruiting
639
Research sites
399
Conditions studied
126
Studies per 100,000 residents
22.2

Conditions being studied

The conditions with the most studies recruiting in the area. A study can be for more than one condition.

  • Leukemia41 studies
  • Breast cancer31 studies
  • Non-Hodgkin's lymphoma31 studies
  • Lung cancer30 studies
  • Overweight and obesity24 studies
  • Multiple myeloma (MM)23 studies
  • Head and neck cancer19 studies
  • Ovarian cancer17 studies
  • Colorectal cancer (bowel cancer)16 studies
  • Heart failure15 studies
  • Inflammatory bowel disease (IBD)13 studies
  • Anemia12 studies
  • Chronic obstructive pulmonary disease (COPD)12 studies
  • Uterine cancer12 studies
  • Kidney cancer11 studies
All 126 conditions
  • Leukemia41
  • Breast cancer31
  • Non-Hodgkin's lymphoma31
  • Lung cancer30
  • Overweight and obesity24
  • Multiple myeloma (MM)23
  • Head and neck cancer19
  • Ovarian cancer17
  • Colorectal cancer (bowel cancer)16
  • Heart failure15
  • Inflammatory bowel disease (IBD)13
  • Anemia12
  • Chronic obstructive pulmonary disease (COPD)12
  • Uterine cancer12
  • Kidney cancer11
  • Narcolepsy11
  • Prostate cancer11
  • Cardiovascular disease10
  • Ischemic heart disease (IHD)10
  • Liver disease10
  • Systemic lupus erythematosus (SLE)10
  • Crohn's disease9
  • Gastric cancer (stomach cancer)9
  • Neuroendocrine tumor9
  • Pancreatic cancer9
  • Rheumatoid arthritis9
  • Skin cancer9
  • Stroke9
  • Type 2 diabetes9
  • Alzheimer's disease8
  • Chronic kidney disease (CKD)8
  • Endometrial cancer8
  • Epilepsy8
  • High blood pressure (hypertension)8
  • Melanoma8
  • Myelodysplastic syndrome (MDS)8
  • Peripheral nerve disease8
  • Asthma7
  • Bladder cancer7
  • Migraine7
  • Sarcoma of soft tissue7
  • Sickle cell disease7
  • Amyloidosis6
  • Cardiomyopathy6
  • Cervical cancer6
  • Osteoarthritis (OA)6
  • Ulcerative colitis (UC)6
  • Atrial fibrillation (AF)5
  • Depressive disorder5
  • Interstitial lung disease5
  • Myelofibrosis5
  • Dry eye syndrome4
  • Esophageal cancer4
  • Fatty liver disease (MASH/NASH)4
  • Graft-versus-host disease4
  • Hypercholesterolemia4
  • Idiopathic inflammatory myopathy4
  • Liver cancer4
  • Multiple sclerosis (MS)4
  • Neuroblastoma4
  • Peripheral vascular disease4
  • Sjogren's syndrome4
  • Alopecia3
  • Brain cancer3
  • Chronic skin ulcer3
  • COVID-193
  • Essential thrombocythemia (ET)3
  • Fallopian tube cancer3
  • Hodgkin's lymphoma3
  • Human immunodeficiency virus infection (HIV)3
  • Psoriasis3
  • Systemic sclerosis3
  • Traumatic brain injury3
  • Actinic keratosis2
  • Acute coronary syndrome2
  • Alopecia areata2
  • Anxiety disorder2
  • Congenital heart disease2
  • Down syndrome2
  • Eczema (atopic dermatitis)2
  • Fabry's disease2
  • Germ cell tumor2
  • Gout2
  • Immune thrombocytopenic purpura (ITP)2
  • Intellectual disability2
  • Juvenile idiopathic arthritis (JIA)2
  • Polycythemia vera2
  • Post-transplant lymphoproliferative disorder2
  • Psoriatic arthritis (PsA)2
  • Psychotic disorder2
  • Schizophrenia2
  • Thrombocytopenia2
  • Thrombotic microangiopathy2
  • Achondroplasia1
  • Axial spondyloarthritis1
  • Beta thalassemia1
  • Biliary tract cancer1
  • Cannabis use disorder1
  • Cluster headaches1
  • Complex regional pain syndrome (CRPS)1
  • Cystic fibrosis1
  • Gastrointestinal stromal tumor1
  • Graves' disease1
  • Growth hormone deficiency1
  • Hemophilia A1
  • Hemophilia B1
  • Hidradenitis suppurativa (HS)1
  • Influenza (flu)1
  • Insomnia1
  • Irritable bowel syndrome (IBS)1
  • Neurofibromatosis1
  • Neurofibromatosis type 1 (NF1)1
  • Neuropathic pain1
  • Obsessive-compulsive disorder (OCD)1
  • Opioid use disorder1
  • Overactive bladder (OAB)1
  • Parkinson's disease (PD)1
  • Polymyalgia rheumatica1
  • Pompe disease1
  • Post-traumatic stress disorder (PTSD)1
  • Primary sclerosing cholangitis1
  • Pulmonary hypertension1
  • Rhabdomyosarcoma1
  • Smoking dependence1
  • Testicular cancer1
  • Vasculitis1

157 more studies are for conditions not yet in our catalog.

Whom the studies accept

The share of the area's studies open to each group. A study can accept several.

  • Adults 18 to 6496%
  • Adults 65 and over86%
  • Children and teens (under 18)18%
  • Healthy volunteers7%
  • Open to all sexes95%
  • Women only4%
  • Men only2%

18 studies are for children only.

Study phases

Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.

  • Phase 17%
  • Phase 1/27%
  • Phase 218%
  • Phase 2/33%
  • Phase 336%
  • Phase 43%
  • No phase (device, behavioral and other studies)14%
  • Not stated13%

Most active research sites

The sites recruiting for the most studies in the area.

  1. Levine Cancer InstituteCharlotte127 studies
  2. Carolinas Medical Center/Levine Cancer InstituteCharlotte70 studies
  3. Novant Health Presbyterian Medical CenterCharlotte51 studies
  4. Atrium Health - Carolinas Medical CenterCharlotte30 studies
  5. Atrium Health Cabarrus/LCI-ConcordConcord29 studies
  6. Monroe Biomedical ResearchMonroe25 studies
  7. Carolina BioOncology InstituteHuntersville20 studies
  8. Atrium Health Pineville/LCI-PinevilleCharlotte17 studies
  9. Atrium Health University City/LCI-UniversityCharlotte16 studies
  10. Atrium Health Union/LCI-UnionMonroe15 studies
  11. Levine Cancer Institute-BallantyneCharlotte15 studies
  12. Levine Cancer Institute-GastonGastonia15 studies
  13. Piedmont HealthcareStatesville14 studies
  14. Levine Cancer Institute-Rock HillRock Hill13 studies
  15. Atrium HealthCharlotte12 studies

Cite these figures

Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.

As text

Source: LocalTrial, Clinical trials in the Charlotte area, https://www.localtrial.com/clinical-trials/north-carolina/charlotte, updated November 12, 2026.

With the link, for a web page

Source: <a href="https://www.localtrial.com/clinical-trials/north-carolina/charlotte">LocalTrial, Clinical trials in the Charlotte area</a>, updated November 12, 2026.

About these figures

Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.

The area is the U.S. Census Bureau's Charlotte-Concord-Gastonia, NC-SC metropolitan area. Residents: 2,883,370, the Census Bureau's latest estimate. Updated November 12, 2026.

These figures describe studies, not advice. Talk to your doctor before joining one.

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Clinical Trials in Charlotte, NC | LocalTrial