Clinical trials near you
Clinical trials in the Charlotte area
639 studies are recruiting volunteers at 399 research sites in the Charlotte-Concord-Gastonia, NC-SC area.
Sites in Charlotte, Huntersville, Rock Hill, Statesville, Salisbury, Matthews and 11 more towns.
#40 in the US for recruiting studies#2 in North Carolina#101 in the US per resident
- Studies recruiting
- 639
- Research sites
- 399
- Conditions studied
- 126
- Studies per 100,000 residents
- 22.2
Conditions being studied
The conditions with the most studies recruiting in the area. A study can be for more than one condition.
- Leukemia41 studies
- Breast cancer31 studies
- Non-Hodgkin's lymphoma31 studies
- Lung cancer30 studies
- Overweight and obesity24 studies
- Multiple myeloma (MM)23 studies
- Head and neck cancer19 studies
- Ovarian cancer17 studies
- Colorectal cancer (bowel cancer)16 studies
- Heart failure15 studies
- Inflammatory bowel disease (IBD)13 studies
- Anemia12 studies
- Chronic obstructive pulmonary disease (COPD)12 studies
- Uterine cancer12 studies
- Kidney cancer11 studies
All 126 conditions
- Leukemia41
- Breast cancer31
- Non-Hodgkin's lymphoma31
- Lung cancer30
- Overweight and obesity24
- Multiple myeloma (MM)23
- Head and neck cancer19
- Ovarian cancer17
- Colorectal cancer (bowel cancer)16
- Heart failure15
- Inflammatory bowel disease (IBD)13
- Anemia12
- Chronic obstructive pulmonary disease (COPD)12
- Uterine cancer12
- Kidney cancer11
- Narcolepsy11
- Prostate cancer11
- Cardiovascular disease10
- Ischemic heart disease (IHD)10
- Liver disease10
- Systemic lupus erythematosus (SLE)10
- Crohn's disease9
- Gastric cancer (stomach cancer)9
- Neuroendocrine tumor9
- Pancreatic cancer9
- Rheumatoid arthritis9
- Skin cancer9
- Stroke9
- Type 2 diabetes9
- Alzheimer's disease8
- Chronic kidney disease (CKD)8
- Endometrial cancer8
- Epilepsy8
- High blood pressure (hypertension)8
- Melanoma8
- Myelodysplastic syndrome (MDS)8
- Peripheral nerve disease8
- Asthma7
- Bladder cancer7
- Migraine7
- Sarcoma of soft tissue7
- Sickle cell disease7
- Amyloidosis6
- Cardiomyopathy6
- Cervical cancer6
- Osteoarthritis (OA)6
- Ulcerative colitis (UC)6
- Atrial fibrillation (AF)5
- Depressive disorder5
- Interstitial lung disease5
- Myelofibrosis5
- Dry eye syndrome4
- Esophageal cancer4
- Fatty liver disease (MASH/NASH)4
- Graft-versus-host disease4
- Hypercholesterolemia4
- Idiopathic inflammatory myopathy4
- Liver cancer4
- Multiple sclerosis (MS)4
- Neuroblastoma4
- Peripheral vascular disease4
- Sjogren's syndrome4
- Alopecia3
- Brain cancer3
- Chronic skin ulcer3
- COVID-193
- Essential thrombocythemia (ET)3
- Fallopian tube cancer3
- Hodgkin's lymphoma3
- Human immunodeficiency virus infection (HIV)3
- Psoriasis3
- Systemic sclerosis3
- Traumatic brain injury3
- Actinic keratosis2
- Acute coronary syndrome2
- Alopecia areata2
- Anxiety disorder2
- Congenital heart disease2
- Down syndrome2
- Eczema (atopic dermatitis)2
- Fabry's disease2
- Germ cell tumor2
- Gout2
- Immune thrombocytopenic purpura (ITP)2
- Intellectual disability2
- Juvenile idiopathic arthritis (JIA)2
- Polycythemia vera2
- Post-transplant lymphoproliferative disorder2
- Psoriatic arthritis (PsA)2
- Psychotic disorder2
- Schizophrenia2
- Thrombocytopenia2
- Thrombotic microangiopathy2
- Achondroplasia1
- Axial spondyloarthritis1
- Beta thalassemia1
- Biliary tract cancer1
- Cannabis use disorder1
- Cluster headaches1
- Complex regional pain syndrome (CRPS)1
- Cystic fibrosis1
- Gastrointestinal stromal tumor1
- Graves' disease1
- Growth hormone deficiency1
- Hemophilia A1
- Hemophilia B1
- Hidradenitis suppurativa (HS)1
- Influenza (flu)1
- Insomnia1
- Irritable bowel syndrome (IBS)1
- Neurofibromatosis1
- Neurofibromatosis type 1 (NF1)1
- Neuropathic pain1
- Obsessive-compulsive disorder (OCD)1
- Opioid use disorder1
- Overactive bladder (OAB)1
- Parkinson's disease (PD)1
- Polymyalgia rheumatica1
- Pompe disease1
- Post-traumatic stress disorder (PTSD)1
- Primary sclerosing cholangitis1
- Pulmonary hypertension1
- Rhabdomyosarcoma1
- Smoking dependence1
- Testicular cancer1
- Vasculitis1
157 more studies are for conditions not yet in our catalog.
Whom the studies accept
The share of the area's studies open to each group. A study can accept several.
- Adults 18 to 6496%
- Adults 65 and over86%
- Children and teens (under 18)18%
- Healthy volunteers7%
- Open to all sexes95%
- Women only4%
- Men only2%
18 studies are for children only.
Study phases
Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.
- Phase 17%
- Phase 1/27%
- Phase 218%
- Phase 2/33%
- Phase 336%
- Phase 43%
- No phase (device, behavioral and other studies)14%
- Not stated13%
Most active research sites
The sites recruiting for the most studies in the area.
- Levine Cancer InstituteCharlotte127 studies
- Carolinas Medical Center/Levine Cancer InstituteCharlotte70 studies
- Novant Health Presbyterian Medical CenterCharlotte51 studies
- Atrium Health - Carolinas Medical CenterCharlotte30 studies
- Atrium Health Cabarrus/LCI-ConcordConcord29 studies
- Monroe Biomedical ResearchMonroe25 studies
- Carolina BioOncology InstituteHuntersville20 studies
- Atrium Health Pineville/LCI-PinevilleCharlotte17 studies
- Atrium Health University City/LCI-UniversityCharlotte16 studies
- Atrium Health Union/LCI-UnionMonroe15 studies
- Levine Cancer Institute-BallantyneCharlotte15 studies
- Levine Cancer Institute-GastonGastonia15 studies
- Piedmont HealthcareStatesville14 studies
- Levine Cancer Institute-Rock HillRock Hill13 studies
- Atrium HealthCharlotte12 studies
Cite these figures
Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.
Source: LocalTrial, Clinical trials in the Charlotte area, https://www.localtrial.com/clinical-trials/north-carolina/charlotte, updated November 12, 2026.
Source: <a href="https://www.localtrial.com/clinical-trials/north-carolina/charlotte">LocalTrial, Clinical trials in the Charlotte area</a>, updated November 12, 2026.
About these figures
Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.
The area is the U.S. Census Bureau's Charlotte-Concord-Gastonia, NC-SC metropolitan area. Residents: 2,883,370, the Census Bureau's latest estimate. Updated November 12, 2026.
These figures describe studies, not advice. Talk to your doctor before joining one.
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