Clinical trials near you
Clinical trials in the Durham area
955 studies are recruiting volunteers at 325 research sites in the Durham-Chapel Hill, NC area.
Sites in Chapel Hill, Durham, Hillsborough, Carrboro.
#26 in the US for recruiting studies#1 in North Carolina#2 in the US per resident
- Studies recruiting
- 955
- Research sites
- 325
- Conditions studied
- 176
- Studies per 100,000 residents
- 153.9
Conditions being studied
The conditions with the most studies recruiting in the area. A study can be for more than one condition.
- Leukemia56 studies
- Breast cancer54 studies
- Lung cancer40 studies
- Non-Hodgkin's lymphoma37 studies
- Multiple myeloma (MM)34 studies
- Head and neck cancer29 studies
- Pancreatic cancer20 studies
- Colorectal cancer (bowel cancer)19 studies
- Uterine cancer19 studies
- Bladder cancer18 studies
- Prostate cancer18 studies
- Cardiovascular disease17 studies
- Neuroendocrine tumor17 studies
- Ovarian cancer17 studies
- Inflammatory bowel disease (IBD)16 studies
All 176 conditions
- Leukemia56
- Breast cancer54
- Lung cancer40
- Non-Hodgkin's lymphoma37
- Multiple myeloma (MM)34
- Head and neck cancer29
- Pancreatic cancer20
- Colorectal cancer (bowel cancer)19
- Uterine cancer19
- Bladder cancer18
- Prostate cancer18
- Cardiovascular disease17
- Neuroendocrine tumor17
- Ovarian cancer17
- Inflammatory bowel disease (IBD)16
- Kidney cancer16
- Liver disease16
- Skin cancer16
- Brain cancer15
- Heart failure15
- Myelodysplastic syndrome (MDS)15
- Overweight and obesity15
- Melanoma14
- Endometrial cancer13
- Chronic kidney disease (CKD)12
- High blood pressure (hypertension)12
- Sarcoma of soft tissue12
- Anemia11
- Myelofibrosis11
- Type 2 diabetes11
- Anxiety disorder10
- Idiopathic inflammatory myopathy10
- Peripheral nerve disease10
- Post-traumatic stress disorder (PTSD)10
- Systemic lupus erythematosus (SLE)10
- Type 1 diabetes10
- Asthma9
- Crohn's disease9
- Depressive disorder9
- Cervical cancer8
- Cystic fibrosis8
- Epilepsy8
- Esophageal cancer8
- Liver cancer8
- Motor neuron disease (MND)8
- Ulcerative colitis (UC)8
- Essential thrombocythemia (ET)7
- Intellectual disability7
- Interstitial lung disease7
- Parkinson's disease (PD)7
- Amyotrophic lateral sclerosis (ALS)6
- Congenital heart disease6
- COVID-196
- Gastric cancer (stomach cancer)6
- Human immunodeficiency virus infection (HIV)6
- Rheumatoid arthritis6
- Stroke6
- Amyloidosis5
- Autism spectrum disorder (ASD)5
- Down syndrome5
- Eating disorder5
- Food allergy5
- Hidradenitis suppurativa (HS)5
- Hodgkin's lymphoma5
- Ischemic heart disease (IHD)5
- Neuroblastoma5
- Polycythemia vera5
- Psoriasis5
- Sickle cell disease5
- Systemic sclerosis5
- Vasculitis5
- Abdominal aortic aneurysm4
- Atrial fibrillation (AF)4
- Cardiomyopathy4
- Chronic obstructive pulmonary disease (COPD)4
- Duchenne muscular dystrophy (DMD)4
- Fallopian tube cancer4
- Huntington's disease (HD)4
- Multiple sclerosis (MS)4
- Osteoarthritis (OA)4
- Peripheral vascular disease4
- Post-transplant lymphoproliferative disorder4
- Psoriatic arthritis (PsA)4
- Pulmonary hypertension4
- Retinal degeneration4
- Urinary incontinence4
- Age-related macular degeneration (AMD)3
- Alzheimer's disease3
- Chronic skin ulcer3
- Cutaneous T-cell lymphoma3
- Esophagitis3
- Fatty liver disease (MASH/NASH)3
- Fibromyalgia3
- Glaucoma3
- Graft-versus-host disease3
- Hearing loss3
- Hypercholesterolemia3
- Influenza (flu)3
- Migraine3
- Ocular hypertension3
- Opioid use disorder3
- Smoking dependence3
- Spinal muscular atrophy (SMA)3
- Testicular cancer3
- Thrombocytopenia3
- Thyroid cancer3
- Attention-deficit hyperactivity disorder (ADHD)2
- Axial spondyloarthritis2
- Biliary tract cancer2
- Cannabis use disorder2
- Facioscapulohumeral muscular dystrophy2
- Frontotemporal dementia (FTD)2
- Gallbladder cancer2
- Gastrointestinal stromal tumor2
- Graves' disease2
- Juvenile idiopathic arthritis (JIA)2
- Low back pain2
- Menopause symptoms2
- Neuromyelitis optica spectrum disorder (NMOSD)2
- Osteoporosis2
- Psychotic disorder2
- Rotator cuff syndrome2
- RSV infection2
- Scoliosis2
- Sleep apnea2
- Ureteral cancer2
- Urethral cancer2
- Uveitis2
- Abdominal cancer1
- Actinic keratosis1
- Alcohol dependence1
- Alopecia1
- Alopecia areata1
- Anal cancer1
- Ankylosing spondylitis1
- Behcet's syndrome1
- Bile duct cancer1
- Bone cyst1
- Chronic cough1
- Chronic sinusitis1
- Complex regional pain syndrome (CRPS)1
- Diabetic eye disease1
- Dry eye syndrome1
- Endometriosis1
- Familial multiple polyposis syndrome1
- Fragile X syndrome1
- Germ cell tumor1
- Hemophilia A1
- Hemophilia B1
- Hepatitis B1
- Immune thrombocytopenic purpura (ITP)1
- Insomnia1
- Irritable bowel syndrome (IBS)1
- Macular edema1
- Mucopolysaccharidosis type II1
- Mucopolysaccharidosis type III1
- Obsessive-compulsive disorder (OCD)1
- Peritoneal cancer1
- Polycystic ovarian syndrome (PCOS)1
- Pompe disease1
- Postnatal depression1
- Prader-Willi syndrome1
- Primary sclerosing cholangitis1
- Progressive supranuclear palsy (PSP)1
- Recurrent urinary tract infection (UTI)1
- Rett's disorder1
- Rhabdomyosarcoma1
- Schizoaffective disorder1
- Schizophrenia1
- Sjogren's syndrome1
- Thrombotic microangiopathy1
- Traumatic brain injury1
- Tricuspid valve regurgitation1
- Vaginal cancer1
- Vascular dementia1
- Vulvar cancer1
284 more studies are for conditions not yet in our catalog.
Whom the studies accept
The share of the area's studies open to each group. A study can accept several.
- Adults 18 to 6493%
- Adults 65 and over81%
- Children and teens (under 18)26%
- Healthy volunteers13%
- Open to all sexes91%
- Women only8%
- Men only1%
57 studies are for children only.
Study phases
Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.
- Early phase 11%
- Phase 16%
- Phase 1/25%
- Phase 218%
- Phase 2/33%
- Phase 321%
- Phase 43%
- No phase (device, behavioral and other studies)25%
- Not stated18%
Most active research sites
The sites recruiting for the most studies in the area.
- University of North Carolina at Chapel HillChapel Hill269 studies
- Duke UniversityDurham125 studies
- University of North Carolina at Chapel HillChapel Hill116 studies
- UNC Lineberger Comprehensive Cancer CenterChapel Hill80 studies
- Durham VA Medical Center, Durham, NCDurham45 studies
- Duke UniversityDurham38 studies
- NIEHS Clinical Research Unit (CRU)Durham11 studies
- University of North Carolina at Chapel HillChapel Hill10 studies
- University of North Carolina-Hillsborough CampusHillsborough10 studies
- Duke UniversityDurham9 studies
- Duke Cancer InstituteDurham8 studies
- UNC Lineberger Comprehensive Cancer CenterChapel Hill8 studies
- UNC- Chapel HillChapel Hill8 studies
- Duke Children's HospitalDurham7 studies
- Duke Vaccine and Trials UnitDurham7 studies
Cite these figures
Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.
Source: LocalTrial, Clinical trials in the Durham area, https://www.localtrial.com/clinical-trials/north-carolina/durham, updated November 12, 2026.
Source: <a href="https://www.localtrial.com/clinical-trials/north-carolina/durham">LocalTrial, Clinical trials in the Durham area</a>, updated November 12, 2026.
About these figures
Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.
The area is the U.S. Census Bureau's Durham-Chapel Hill, NC metropolitan area. Residents: 620,522, the Census Bureau's latest estimate. Updated November 12, 2026.
These figures describe studies, not advice. Talk to your doctor before joining one.
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