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Clinical trials in the Raleigh area

250 studies are recruiting volunteers at 185 research sites in the Raleigh-Cary, NC area.

Sites in Raleigh, Cary, Morrisville, Wake Forest, Smithfield, Garner and 2 more towns.

#67 in the US for recruiting studies#3 in North Carolina#137 in the US per resident

Studies recruiting
250
Research sites
185
Conditions studied
92
Studies per 100,000 residents
16

Conditions being studied

The conditions with the most studies recruiting in the area. A study can be for more than one condition.

  • Age-related macular degeneration (AMD)15 studies
  • Retinal degeneration14 studies
  • Breast cancer11 studies
  • Overweight and obesity10 studies
  • Liver disease9 studies
  • Heart failure8 studies
  • Lung cancer8 studies
  • Bladder cancer7 studies
  • Multiple sclerosis (MS)7 studies
  • Type 2 diabetes7 studies
  • Colorectal cancer (bowel cancer)6 studies
  • Ischemic heart disease (IHD)6 studies
  • Macular edema6 studies
  • Uterine cancer6 studies
  • Cardiovascular disease5 studies
All 92 conditions
  • Age-related macular degeneration (AMD)15
  • Retinal degeneration14
  • Breast cancer11
  • Overweight and obesity10
  • Liver disease9
  • Heart failure8
  • Lung cancer8
  • Bladder cancer7
  • Multiple sclerosis (MS)7
  • Type 2 diabetes7
  • Colorectal cancer (bowel cancer)6
  • Ischemic heart disease (IHD)6
  • Macular edema6
  • Uterine cancer6
  • Cardiovascular disease5
  • Diabetic eye disease5
  • Endometrial cancer5
  • Fatty liver disease (MASH/NASH)5
  • High blood pressure (hypertension)5
  • Inflammatory bowel disease (IBD)5
  • Ovarian cancer5
  • Peripheral vascular disease5
  • Chronic kidney disease (CKD)4
  • Depressive disorder4
  • Graves' disease4
  • Migraine4
  • Peripheral nerve disease4
  • Stroke4
  • Chronic obstructive pulmonary disease (COPD)3
  • Chronic skin ulcer3
  • Crohn's disease3
  • Epilepsy3
  • Leukemia3
  • Prostate cancer3
  • Psoriasis3
  • Ulcerative colitis (UC)3
  • Alzheimer's disease2
  • Eczema (atopic dermatitis)2
  • Fallopian tube cancer2
  • Kidney cancer2
  • Liver cancer2
  • Narcolepsy2
  • Neuroendocrine tumor2
  • Non-Hodgkin's lymphoma2
  • Systemic lupus erythematosus (SLE)2
  • Abdominal aortic aneurysm1
  • Alopecia1
  • Alopecia areata1
  • Amyloidosis1
  • Anemia1
  • Atrial fibrillation (AF)1
  • Bipolar disorder1
  • Cannabis use disorder1
  • Cervical cancer1
  • Cutaneous T-cell lymphoma1
  • Dry eye syndrome1
  • Eating disorder1
  • Endometriosis1
  • Essential thrombocythemia (ET)1
  • Friedreich ataxia1
  • Hemophilia A1
  • Hodgkin's lymphoma1
  • Hypercholesterolemia1
  • Hypothyroidism1
  • Influenza (flu)1
  • Intellectual disability1
  • Interstitial lung disease1
  • Melanoma1
  • Multiple myeloma (MM)1
  • Myelodysplastic syndrome (MDS)1
  • Myelofibrosis1
  • Neuropathic pain1
  • Opioid use disorder1
  • Osteoarthritis (OA)1
  • Overactive bladder (OAB)1
  • Pancreatic cancer1
  • Parkinson's disease (PD)1
  • Polycythemia vera1
  • Post-transplant lymphoproliferative disorder1
  • Post-traumatic stress disorder (PTSD)1
  • Prader-Willi syndrome1
  • Psoriatic arthritis (PsA)1
  • Pulmonary hypertension1
  • Schizophrenia1
  • Sickle cell disease1
  • Skin cancer1
  • Sleep apnea1
  • Tenosynovitis1
  • Traumatic brain injury1
  • Type 1 diabetes1
  • Vulvar cancer1
  • Vulvovaginal candidiasis (thrush)1

66 more studies are for conditions not yet in our catalog.

Whom the studies accept

The share of the area's studies open to each group. A study can accept several.

  • Adults 18 to 6498%
  • Adults 65 and over91%
  • Children and teens (under 18)12%
  • Healthy volunteers8%
  • Open to all sexes88%
  • Women only10%
  • Men only1%

2 studies are for children only.

Study phases

Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.

  • Phase 12%
  • Phase 1/24%
  • Phase 216%
  • Phase 2/33%
  • Phase 342%
  • Phase 42%
  • No phase (device, behavioral and other studies)14%
  • Not stated17%

Most active research sites

The sites recruiting for the most studies in the area.

  1. WakeMedRaleigh27 studies
  2. Duke Cancer Center RaleighRaleigh20 studies
  3. Duke Women's Cancer Care RaleighRaleigh18 studies
  4. Duke Cancer Center CaryCary16 studies
  5. NC Heart and Vascular ResearchRaleigh14 studies
  6. Science 37Morrisville10 studies
  7. North Carolina Retina AssociatesWake Forest9 studies
  8. UNC Health Cancer Care RaleighRaleigh5 studies
  9. Velocity Clinical ResearchRaleigh5 studies
  10. Accellacare of RaleighRaleigh4 studies
  11. Duke Raleigh HospitalRaleigh4 studies
  12. Eximia Research NCRaleigh4 studies
  13. M3 Wake Research, Inc.Raleigh4 studies
  14. NC Retina AssociatesWake Forest4 studies
  15. North Carolina Retina Associates (Cary)Cary4 studies

Cite these figures

Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.

As text

Source: LocalTrial, Clinical trials in the Raleigh area, https://www.localtrial.com/clinical-trials/north-carolina/raleigh, updated November 12, 2026.

With the link, for a web page

Source: <a href="https://www.localtrial.com/clinical-trials/north-carolina/raleigh">LocalTrial, Clinical trials in the Raleigh area</a>, updated November 12, 2026.

About these figures

Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.

The area is the U.S. Census Bureau's Raleigh-Cary, NC metropolitan area. Residents: 1,562,009, the Census Bureau's latest estimate. Updated November 12, 2026.

These figures describe studies, not advice. Talk to your doctor before joining one.

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