Clinical trials near you
Clinical trials in the Charleston area
688 studies are recruiting volunteers at 267 research sites in the Charleston-North Charleston, SC area.
Sites in Charleston, Mount Pleasant, Summerville, North Charleston, Ladson, Awendaw and 3 more towns.
#38 in the US for recruiting studies#1 in South Carolina#5 in the US per resident
- Studies recruiting
- 688
- Research sites
- 267
- Conditions studied
- 143
- Studies per 100,000 residents
- 79.1
Conditions being studied
The conditions with the most studies recruiting in the area. A study can be for more than one condition.
- Lung cancer26 studies
- Head and neck cancer25 studies
- Stroke22 studies
- Breast cancer21 studies
- Prostate cancer21 studies
- Heart failure20 studies
- Liver disease20 studies
- Overweight and obesity20 studies
- Depressive disorder19 studies
- Leukemia17 studies
- Cardiovascular disease16 studies
- Post-traumatic stress disorder (PTSD)16 studies
- Age-related macular degeneration (AMD)15 studies
- High blood pressure (hypertension)15 studies
- Interstitial lung disease15 studies
All 143 conditions
- Lung cancer26
- Head and neck cancer25
- Stroke22
- Breast cancer21
- Prostate cancer21
- Heart failure20
- Liver disease20
- Overweight and obesity20
- Depressive disorder19
- Leukemia17
- Cardiovascular disease16
- Post-traumatic stress disorder (PTSD)16
- Age-related macular degeneration (AMD)15
- High blood pressure (hypertension)15
- Interstitial lung disease15
- Retinal degeneration15
- Inflammatory bowel disease (IBD)14
- Parkinson's disease (PD)13
- Non-Hodgkin's lymphoma12
- Anxiety disorder11
- Ovarian cancer11
- Cystic fibrosis10
- Kidney cancer10
- Colorectal cancer (bowel cancer)9
- Crohn's disease9
- Skin cancer9
- Smoking dependence9
- Type 2 diabetes9
- Bladder cancer8
- Cardiomyopathy8
- Pancreatic cancer8
- Pulmonary hypertension8
- Sarcoma of soft tissue8
- Cannabis use disorder7
- Opioid use disorder7
- Systemic lupus erythematosus (SLE)7
- Ulcerative colitis (UC)7
- Alpha-1-antitrypsin deficiency (AATD)6
- Anemia6
- Attention-deficit hyperactivity disorder (ADHD)6
- Congenital heart disease6
- Diabetic eye disease6
- Ischemic heart disease (IHD)6
- Melanoma6
- Myelodysplastic syndrome (MDS)6
- Neuroendocrine tumor6
- Alcohol dependence5
- Atrial fibrillation (AF)5
- Chronic obstructive pulmonary disease (COPD)5
- Fatty liver disease (MASH/NASH)5
- Macular edema5
- Multiple myeloma (MM)5
- Peripheral nerve disease5
- Uterine cancer5
- Brain cancer4
- Cervical cancer4
- Chronic kidney disease (CKD)4
- Eczema (atopic dermatitis)4
- Esophageal cancer4
- Fallopian tube cancer4
- Liver cancer4
- Myelofibrosis4
- Narcolepsy4
- Neuroblastoma4
- Osteoarthritis (OA)4
- Systemic sclerosis4
- Alopecia3
- Amyloidosis3
- COVID-193
- Endometrial cancer3
- Gastric cancer (stomach cancer)3
- Graft-versus-host disease3
- Idiopathic inflammatory myopathy3
- Influenza (flu)3
- Insomnia3
- Neuropathic pain3
- Rheumatoid arthritis3
- Tricuspid valve regurgitation3
- Acne2
- Alzheimer's disease2
- Asthma2
- Eating disorder2
- Epidermolysis bullosa2
- Epilepsy2
- Glaucoma2
- Gout2
- Graves' disease2
- Hearing loss2
- Hidradenitis suppurativa (HS)2
- Hodgkin's lymphoma2
- Human immunodeficiency virus infection (HIV)2
- Migraine2
- Motor neuron disease (MND)2
- Ocular hypertension2
- Overactive bladder (OAB)2
- Peripheral vascular disease2
- Postnatal depression2
- Primary biliary cholangitis (PBC)2
- Psoriasis2
- Sickle cell disease2
- Spinal muscular atrophy (SMA)2
- Traumatic brain injury2
- Abdominal aortic aneurysm1
- Abdominal cancer1
- Actinic keratosis1
- Alopecia areata1
- Anal cancer1
- Ankylosing spondylitis1
- Autism spectrum disorder (ASD)1
- Axial spondyloarthritis1
- Biliary tract cancer1
- Chronic cough1
- Chronic sinusitis1
- Down syndrome1
- Dry eye syndrome1
- Endometriosis1
- Esophagitis1
- Fibromyalgia1
- Food allergy1
- Germ cell tumor1
- Hemolytic uremic syndrome1
- Hypothyroidism1
- Intellectual disability1
- Juvenile idiopathic arthritis (JIA)1
- Low back pain1
- Multiple sclerosis (MS)1
- Obsessive-compulsive disorder (OCD)1
- Peritoneal cancer1
- Post-transplant lymphoproliferative disorder1
- Primary sclerosing cholangitis1
- Psoriatic arthritis (PsA)1
- Rhabdomyosarcoma1
- Rotator cuff syndrome1
- Scoliosis1
- Sjogren's syndrome1
- Sleep apnea1
- Spasmodic torticollis1
- Thrombocytopenia1
- Thrombotic microangiopathy1
- Thyroid cancer1
- Urethral cancer1
- Urinary incontinence1
- Vasculitis1
172 more studies are for conditions not yet in our catalog.
Whom the studies accept
The share of the area's studies open to each group. A study can accept several.
- Adults 18 to 6493%
- Adults 65 and over84%
- Children and teens (under 18)18%
- Healthy volunteers9%
- Open to all sexes94%
- Women only3%
- Men only3%
47 studies are for children only.
Study phases
Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.
- Early phase 11%
- Phase 13%
- Phase 1/23%
- Phase 217%
- Phase 2/34%
- Phase 331%
- Phase 43%
- No phase (device, behavioral and other studies)25%
- Not stated12%
Most active research sites
The sites recruiting for the most studies in the area.
- Medical University of South CarolinaCharleston408 studies
- Ralph H. Johnson VA Medical Center, Charleston, SCCharleston30 studies
- Coastal Carolina Research CenterNorth Charleston17 studies
- Medical University of South CarolinaCharleston14 studies
- Charleston Neuroscience InstituteCharleston10 studies
- Medical University of South CarolinaCharleston9 studies
- MUSC-Hollings Cancer CenterCharleston8 studies
- Medical University of South CarolinaCharleston6 studies
- Clinical Trials of South CarolinaCharleston5 studies
- Charleston Neuroscience Institute, LLCMount Pleasant4 studies
- Coastal Carolina Research CtrNorth Charleston4 studies
- Lowcountry Lung and Critical Care, PACharleston4 studies
- Medical University of South CarolinaCharleston4 studies
- National Allergy and Asthma Research LLSNorth Charleston4 studies
- Ralph H. Johnson VA Health Care SystemCharleston4 studies
Cite these figures
Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.
Source: LocalTrial, Clinical trials in the Charleston area, https://www.localtrial.com/clinical-trials/south-carolina/charleston, updated November 12, 2026.
Source: <a href="https://www.localtrial.com/clinical-trials/south-carolina/charleston">LocalTrial, Clinical trials in the Charleston area</a>, updated November 12, 2026.
About these figures
Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.
The area is the U.S. Census Bureau's Charleston-North Charleston, SC metropolitan area. Residents: 869,940, the Census Bureau's latest estimate. Updated November 12, 2026.
These figures describe studies, not advice. Talk to your doctor before joining one.
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