Clinical trials near you
Clinical trials in the Columbia area
175 studies are recruiting volunteers at 78 research sites in the Columbia, SC area.
Sites in Columbia, West Columbia, Lexington.
#86 in the US for recruiting studies#3 in South Carolina#114 in the US per resident
- Studies recruiting
- 175
- Research sites
- 78
- Conditions studied
- 74
- Studies per 100,000 residents
- 20.1
Conditions being studied
The conditions with the most studies recruiting in the area. A study can be for more than one condition.
- Age-related macular degeneration (AMD)10 studies
- Retinal degeneration10 studies
- Narcolepsy9 studies
- Overweight and obesity9 studies
- Liver disease8 studies
- Stroke8 studies
- Chronic kidney disease (CKD)7 studies
- Fatty liver disease (MASH/NASH)7 studies
- Breast cancer6 studies
- Heart failure6 studies
- High blood pressure (hypertension)6 studies
- Leukemia6 studies
- Non-Hodgkin's lymphoma6 studies
- Cardiovascular disease5 studies
- Lung cancer5 studies
All 74 conditions
- Age-related macular degeneration (AMD)10
- Retinal degeneration10
- Narcolepsy9
- Overweight and obesity9
- Liver disease8
- Stroke8
- Chronic kidney disease (CKD)7
- Fatty liver disease (MASH/NASH)7
- Breast cancer6
- Heart failure6
- High blood pressure (hypertension)6
- Leukemia6
- Non-Hodgkin's lymphoma6
- Cardiovascular disease5
- Lung cancer5
- Urinary incontinence5
- Kidney cancer4
- Macular edema4
- Overactive bladder (OAB)4
- Type 2 diabetes4
- Chronic obstructive pulmonary disease (COPD)3
- Growth hormone deficiency3
- Inflammatory bowel disease (IBD)3
- Interstitial lung disease3
- Ischemic heart disease (IHD)3
- Neuroblastoma3
- Sarcoma of soft tissue3
- Bladder cancer2
- Colorectal cancer (bowel cancer)2
- Congenital heart disease2
- Diabetic eye disease2
- Down syndrome2
- Head and neck cancer2
- Insomnia2
- Intellectual disability2
- Melanoma2
- Neuroendocrine tumor2
- Peripheral vascular disease2
- Skin cancer2
- Sleep apnea2
- Ulcerative colitis (UC)2
- Alzheimer's disease1
- Atrial fibrillation (AF)1
- Autism spectrum disorder (ASD)1
- Celiac disease1
- Chronic idiopathic urticaria (hives)1
- Crohn's disease1
- Cystic fibrosis1
- Depressive disorder1
- Endometrial cancer1
- Endometriosis1
- Esophageal cancer1
- Fallopian tube cancer1
- Fibromyalgia1
- Gastric cancer (stomach cancer)1
- Germ cell tumor1
- Gout1
- Hodgkin's lymphoma1
- Huntington's disease (HD)1
- Liver cancer1
- Myelodysplastic syndrome (MDS)1
- Osteoarthritis (OA)1
- Ovarian cancer1
- Pancreatic cancer1
- Post-transplant lymphoproliferative disorder1
- Postnatal depression1
- Prostate cancer1
- Psoriasis1
- Psychotic disorder1
- Pulmonary hypertension1
- Rhabdomyosarcoma1
- Rheumatoid arthritis1
- Systemic lupus erythematosus (SLE)1
- Uterine cancer1
45 more studies are for conditions not yet in our catalog.
Whom the studies accept
The share of the area's studies open to each group. A study can accept several.
- Adults 18 to 6490%
- Adults 65 and over72%
- Children and teens (under 18)31%
- Healthy volunteers9%
- Open to all sexes96%
- Women only3%
- Men only1%
17 studies are for children only.
Study phases
Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.
- Phase 11%
- Phase 1/22%
- Phase 215%
- Phase 2/34%
- Phase 339%
- Phase 42%
- No phase (device, behavioral and other studies)26%
- Not stated11%
Most active research sites
The sites recruiting for the most studies in the area.
- Prisma Health Richland HospitalColumbia50 studies
- University of South CarolinaColumbia13 studies
- Bogan Sleep Consultants, LLCColumbia9 studies
- Lexington Medical CenterWest Columbia7 studies
- Southern UrogynecologyWest Columbia7 studies
- Prisma Health - MidlandsColumbia6 studies
- Lexington HealthWest Columbia5 studies
- ObjectiveHealth-Columbia Digestive Health ResearchColumbia5 studies
- Palmetto Retina Center, LLCWest Columbia5 studies
- Columbia Dermatology & AestheticsColumbia4 studies
- Palmetto Retina Center (West Columbia)West Columbia4 studies
- University of South CarolinaColumbia3 studies
- 89bio Clinical Study SiteColumbia2 studies
- Columbia VA Health Care System/Dorn VA Medical CenterColumbia2 studies
- Columbia, South CarolinaColumbia2 studies
Cite these figures
Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.
Source: LocalTrial, Clinical trials in the Columbia area, https://www.localtrial.com/clinical-trials/south-carolina/columbia, updated November 12, 2026.
Source: <a href="https://www.localtrial.com/clinical-trials/south-carolina/columbia">LocalTrial, Clinical trials in the Columbia area</a>, updated November 12, 2026.
About these figures
Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.
The area is the U.S. Census Bureau's Columbia, SC metropolitan area. Residents: 870,193, the Census Bureau's latest estimate. Updated November 12, 2026.
These figures describe studies, not advice. Talk to your doctor before joining one.
Tell us a little about yourself and we'll suggest the studies near you that may fit. Free and private.
Ready to see what's near you?
Get matched