Clinical trials near you
Clinical trials in the Knoxville area
207 studies are recruiting volunteers at 98 research sites in the Knoxville, TN area.
Sites in Knoxville, Oak Ridge, Maryville, Powell, Alcoa, Harriman and 1 more towns.
#75 in the US for recruiting studies#3 in Tennessee#106 in the US per resident
- Studies recruiting
- 207
- Research sites
- 98
- Conditions studied
- 70
- Studies per 100,000 residents
- 21.6
Conditions being studied
The conditions with the most studies recruiting in the area. A study can be for more than one condition.
- Lung cancer19 studies
- Breast cancer13 studies
- Overweight and obesity10 studies
- Neuroendocrine tumor8 studies
- High blood pressure (hypertension)7 studies
- Interstitial lung disease7 studies
- Leukemia7 studies
- Melanoma7 studies
- Non-Hodgkin's lymphoma7 studies
- Skin cancer7 studies
- Head and neck cancer6 studies
- Heart failure6 studies
- Ischemic heart disease (IHD)6 studies
- Type 2 diabetes6 studies
- Cardiovascular disease5 studies
All 70 conditions
- Lung cancer19
- Breast cancer13
- Overweight and obesity10
- Neuroendocrine tumor8
- High blood pressure (hypertension)7
- Interstitial lung disease7
- Leukemia7
- Melanoma7
- Non-Hodgkin's lymphoma7
- Skin cancer7
- Head and neck cancer6
- Heart failure6
- Ischemic heart disease (IHD)6
- Type 2 diabetes6
- Cardiovascular disease5
- Chronic obstructive pulmonary disease (COPD)5
- Kidney cancer5
- Multiple sclerosis (MS)5
- Chronic kidney disease (CKD)4
- Ovarian cancer4
- Pancreatic cancer4
- Pulmonary hypertension4
- Sarcoma of soft tissue4
- Colorectal cancer (bowel cancer)3
- Down syndrome3
- Intellectual disability3
- Liver cancer3
- Liver disease3
- Peripheral vascular disease3
- Stroke3
- Acute coronary syndrome2
- Age-related macular degeneration (AMD)2
- Alzheimer's disease2
- Amyotrophic lateral sclerosis (ALS)2
- Anxiety disorder2
- Bladder cancer2
- Depressive disorder2
- Gastric cancer (stomach cancer)2
- Gastrointestinal stromal tumor2
- Gestational diabetes2
- Hypercholesterolemia2
- Influenza (flu)2
- Motor neuron disease (MND)2
- Myelodysplastic syndrome (MDS)2
- Neuroblastoma2
- Peripheral nerve disease2
- Prostate cancer2
- Retinal degeneration2
- Rhabdomyosarcoma2
- Uterine cancer2
- Actinic keratosis1
- Alopecia1
- Amyloidosis1
- Anemia1
- Atrial fibrillation (AF)1
- Biliary tract cancer1
- Cervical cancer1
- Crohn's disease1
- Diabetic eye disease1
- Endometrial cancer1
- Fibromyalgia1
- Germ cell tumor1
- Hodgkin's lymphoma1
- Inflammatory bowel disease (IBD)1
- Irritable bowel syndrome (IBS)1
- Macular edema1
- Post-transplant lymphoproliferative disorder1
- RSV infection1
- Smoking dependence1
- Ulcerative colitis (UC)1
46 more studies are for conditions not yet in our catalog.
Whom the studies accept
The share of the area's studies open to each group. A study can accept several.
- Adults 18 to 6497%
- Adults 65 and over83%
- Children and teens (under 18)18%
- Healthy volunteers7%
- Open to all sexes94%
- Women only5%
- Men only1%
2 studies are for children only.
Study phases
Earlier phases test safety in fewer people; later phases compare a treatment with the usual care in many.
- Phase 13%
- Phase 1/23%
- Phase 214%
- Phase 2/35%
- Phase 350%
- Phase 42%
- No phase (device, behavioral and other studies)13%
- Not stated10%
Most active research sites
The sites recruiting for the most studies in the area.
- University of Tennessee Medical CenterKnoxville52 studies
- East Tennessee Childrens HospitalKnoxville27 studies
- Tennessee Cancer SpecialistsKnoxville13 studies
- University of Tennessee - KnoxvilleKnoxville13 studies
- Tennova Healthcare - Turkey Creek Medical CenterKnoxville6 studies
- Fort Sanders Regional Medical CenterKnoxville5 studies
- Alliance for Multispecialty Research, LLCKnoxville4 studies
- Knoxville Kidney Center PLLCKnoxville4 studies
- StatCare Pulmonary Consultants, PLLCKnoxville4 studies
- Thompson Proton CenterKnoxville4 studies
- Alliance for Multispecialty Research - KnoxvilleKnoxville3 studies
- New Phase Research and DevelopmentKnoxville3 studies
- Parkwest Medical CenterKnoxville3 studies
- Southeastern Retina Associates, P.C.Knoxville3 studies
- Thompson Cancer Survival CenterKnoxville3 studies
Cite these figures
Free to use under CC BY 4.0. Please credit LocalTrial with a link to this page.
Source: LocalTrial, Clinical trials in the Knoxville area, https://www.localtrial.com/clinical-trials/tennessee/knoxville, updated November 12, 2026.
Source: <a href="https://www.localtrial.com/clinical-trials/tennessee/knoxville">LocalTrial, Clinical trials in the Knoxville area</a>, updated November 12, 2026.
About these figures
Counted from ClinicalTrials.gov, the U.S. registry of clinical studies, for studies recruiting in the United States. A study is counted once however many sites it has in the area.
The area is the U.S. Census Bureau's Knoxville, TN metropolitan area. Residents: 957,608, the Census Bureau's latest estimate. Updated November 12, 2026.
These figures describe studies, not advice. Talk to your doctor before joining one.
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